Hard fat with softer consistency, similar to natural lard, but stable, odourless, emollient in creams, capsule filling mass. Batch k was prepared by weighing out the cod liver oil, tween 20, saccharine sodium, softisan 378 and miglyol 812 into a suitable container. It is the perfect base for pasty product concepts like lip products or body butters, as it imparts structure and body to the product yet creates a surprisingly light skin feel. It is a blend of triglycerides based on saturated evennumbered. An exclusive store of free software and ebook with freelancing tips. For the main semisolid lipid s701, the viscosity of the overall semisolid vehicle reduced from 563 cps for neat s701 to 427 cps and 295 cps respectively after being modified with 10 wt.
Softisan 378 can be easily incorporated, either in molten or cold state, in creams, lotions and pastes. Softisan manufacturers suppliers of softisan product. Therapeutic effects of prolonged cannabidiol treatment on. These ingredients were warmed to between 40 and 45 c.
The information and materials provided is for educational purposes only. Whereisitis an application written for windows operating systems, and designed to help you maintain and organize a catalog of your computer media collection, including cdroms and dvds, audio cds, diskettes, removable drives, hard drives, network drives, remote file servers, or any other present or future storage media device windows can access as a. It is a consistency regulator and show less greasy sheen. With its low melting point, it leaves a nontacky and nongreasy film on the skin. Scan to pdf as a replacement for softi were a completely separate company to softi. Capsaicinloaded sln were prepared from dynasan 116 and softisan 378 and their physicochemical properties were investigated and compared with a nanoemulsion prepared from miglyol 812. Register once for the softing customer portal and you will be able to use a range of services without having to reenter your data. Because of its composition softisan 378 exhibits a long shelf life without a risk of rancidity. Softisan multifunctionals the warner graham company.
Occlusion factor of sln was greater than nanoemulsions and showed. Covers information required for the production of drawings related to buildings and their services. Softisan 378 is a hard fat with softer consistency, similar to natural lard, but stable, odourless, emollient in creams, capsule filling mass. At bl and each weekly session, participants received 28 gelatincoated capsules containing 50 mg of 99. For the main semisolid lipid s701, the viscosity of.
Solidata pdf writer installs an additional virtual printer which can be used to save pdf. Preparation of ultrafine powders from polysaccharidecoated solid lipid nanoparticles and nanostructured lipid carriers by innovative nano spray drying technology. Glycerides, c12c18 mono and di, glyceryl stearate, peg4, polyoxyethylene 25 cetyl stearyl ether, peg32, peg6, medium chain triglycerides, glyceryl ricinoleate stabilized. Its similar to lard in consistency, but has a superior oxidation stability and product. About us we believe everything in the internet must be free. The mean particle sizes of all lipid nanoparticles were in the range of 160340 nm with the pdi between 0. The invention specifically provides a hydrophobic matrix for formulation with topotecan hc1 that is dispersed so as to minimize any chemical reaction between the active drug, the excipients and ambient moisture. Treatment of psoriasis use advantan ointment, fatty ointment or cream once or twice a day on the patches of psoriasis.
It is similar to lard in consistency, but has a superior oxidation stability. To go further in meeting our customers needs, certificates of analysis coa, material safety data sheets msds, and technical specifications are available for all our products online or upon request. A featurerich product first introduced in 1997, fileup is the one solution that offers both clientside resumability and the strength to overcome the builtin file. Softisan 649 is a partial ester of diglycerin with medium chain fatty acids, isostearic acid, stearic acid, 12hydroxystearic acid and adipic acid. Influence of state and crystallinity of lipid matrix on physicochemical. When you see the dialog box like the one in the image below click on the run button. Wo1999006031a1 pharmaceutical formulation for camptothecin. Sasols softisan 649 is a partial ester of diglycerin with medium chain fatty acids, isostearic acid, 12hydroxystearic acid and adipic acid. Softisan 100 by ioi oleo acts as a fats consistency agent. The effect of different wall materials on the production of. It is free from antioxidants and other stabilizing additives.
It is a blend of triglycerides based on saturated evennumbered, unbranched natural fatty acids of vegetable origin. The purpose of this study was to evaluate the influence of crystallinity and state of lipid matrix on the physicochemical properties and in vitro skin permeation of capsaicinloaded lipid nanoparticles. The product does not contain any additives such as antioxidants, preservatives or others. Use pdf download to do whatever you like with pdf files on the web and regain control. With our two modern production facilities in germany with a combined capacity of more than 20. A veterinary drug delivery system suitable for oral administration to animals comprising a suitable medication, a nonvolatile oil, silicone dioxide, capriccaprylic triglyceride andor capriccaprylicstearic triglyceride. The invention relates to a stable topotecan pharmaceutical composition in the form of a gelatin capsule. They are characterized by their exceptional hardness at room temperature and their sharp melting range. All software downloads p software free download soft32.
Certificate of analysis reference code no 3271 708826 analysed according to. As far as we are aware softi are no longer trading. The fatty acids used for the production of softisan 378 comply with cfr 21, 172. In the personal care division of ioi oleo gmbh, we have decades of experience in the production and application of specialties for cosmetics. Customers should always refer to the ingredients label as affixed to each product or the material safety data sheet specification sheet which are current at the time of supply of the product.
Puncto rub cream peppermint oil, eucalyptus oil, rosemary oil read all of this leaflet carefully because it contains important information for you. Softisan 100 is one of three softisan hard fat types, which are white masses with a neutral odor and taste. Preparation of ultrafine powders from polysaccharide. Witepsol s and softisan 378 are used in pharmaceutical dosage forms such as chewable tablets, e. The lower permeation of capsaicin from softisan 378 sln is likely due to the presence of supercooled melts property. Web to pdfconvert any web pages to highquality pdf. Safety data sheet according to 19072006ec, article 31. Patient information sheet softisan 649 s016 your patch testing results indicate that you have a contact allergy to softisan 649. Their versatile properties their versatile properties including refatting, wetting performance and antimicrobial activity make them multifunctional ingredients for a variety of personal care and cos. Select fire fighting measures suitable to surrounding environment. It is a nonanimal derived, vegetablebased semisolid lanolin substitute with high waterbinding capacity and good adhesion to the skin. Following the application of centany mupirocin ointment,2% to a 400 cm 2 area on the back of 23 healthy volunteers once daily for 7 days, the mean range cumulative urinary excretion of monic acid over 24 hrs following the last administration was 1. Softisan 378 emollient by ioi oleo technical datasheet. Of course, if you are using the softi software in your business and cant get help or advice about the software then that could cause problems for you were you to need support.
Compared to softisan 378 sln at 2 and 8 h, the amount of capsaicin in receptor medium of miglyol 812 ne was higher due to the liquid state of nanoemulsion providing the higher release of capsaicin. Feb, 2007 each gram of centany mupirocin ointment,2% contains 20 mg mupirocin in a soft white ointment base consisting of castor oil, oleyl alcohol, hard fat softisan 378 and propylene glycol monostearate. Safety data sheet according to 19072006 eec article 31 38. Softisan 378 is a semisolid emollient with a low melting point that leaves a nontacky and nongreasy film on the skin. However, you still need to use puncto rub carefully to get the best results from it.
Softisan 649 by ioi oleo acts as a filmforming agent. Preparation of ultrafine powders from polysaccharidecoated. The small interval between melting and solidification points allows a. Advantan lotion apply thinly to the affected area of skin and gently rub in. Only needing to type and edit text files, you can create html help files, website help systems, ebooks, faqs and single htmlscan be converted to doc and pdf.
Softisan 378, a fat with a consistency similar to natural lard. The softisan melted, and an opaque solution was obtained. Their versatile properties including refatting, wetting performance and antimicrobial activity make them multifunctional ingredients for a variety of personal care and cos. Softisan 378 sln exhibited supercooled melts with low occlusion and skin permeation. Softisan 378 is a specialty blend of triglycerides based on saturated evennumbered, unbranched natural fatty acids of vegetable origin. The invention specifically provides a hydrophobic matrix for formulation with topotecan hc1 that is dispersed so as to minimize any chemical reaction between the active drug, the. Softisan 649 is a yellowish, pasty, tacky, very stringy substance. Cosmetics formulary 012012 foreword sasol is a leading producer of raw materials for cosmetics and personal care. The small interval between melting and solidification points allows a rapid and economic processing. Intern tests requirement result unit standard remark appearance white mass with a characteristic conform neutral odour conform. The product is nonocclusive and in comparison to lanolin oil virtual odorless. Softi scan to pdf full download legit download video.
Adjustment to regulation ec 19072006 reach and ghslabelling system. It is important that you familiarize yourself with this chemical and take steps to avoid coming in contact with it. Our brands stand for proven quality, unique performance, and perceivable benefits in the final formulation. Softisan 100 is used in emulsions, liquid products oils and solid sticks.
Treatment of eczema use advantan once a day to treat the affected skin. Request pdf on jul 1, 2016, taoran wang and others published preparation of ultrafine powders from polysaccharidecoated solid lipid nanoparticles and nanostructured lipid carriers by. Softisan 649 is used in baby care, lip products, protective creams and sun care. Us5122377a oral delivery system for veterinary drugs. Softisan 649,vegan lanolin substitute alexmo cosmetics. Flavorings can be added to enhance the taste, however, even without extra flavorings the drug delivery system in administrable form is palatable. This collection of guideline formulation examples provides an overview of how the wide range of sasol raw materials can be used to fulfil your performance and formulation requirements. Softisan 378, manufactured by sasol, is a specialty blend of triglycerides based on saturated evennumbered, unbranched natural fatty acids of vegetable origin with a chain length of c8 c18. The monic acid concentration in urine collected at specified intervals for 24 hrs on. The excellent skin compatibility is proven and allergic skin reactions are not reported. Softisan 649 is used as a lanolin substitute and as a cream base in cosmetics, skin care, baby creams, decorative cosmetics and hair care products. Influence of state and crystallinity of lipid matrix on. Softisan 649 is a semisolid lanolin substitute with high water binding capacity and good adhesion to skin. The effect of different wall materials on the production.
Repeated filling in of forms is a thing of the past, whether you wish to subscribe to a newsletter, download a software trial or read one of our white papers. Softisan 378 triglyceride mixture derived form selected saturated c8c10 coconut oil fatty acids dynamit. Longacting semisolid lipid formulations mira pharma. Individuals receiving this information must utilize their independent judgment in determining. It merges a whole series of documents into one pdf file is particularly neat and proves much more reliable than importing separate pdf files into acrobat which sometimes produces unexpected problems. Softisan gc8 and softisan pg2 c10 can be used in emulsions, surfactantbased or hydroalcoholic formulations.
Dac pasta cordes softisan 378 neutralfett fur wasserfreie salben softisan 601 emulsificans nonionicum. The aim of this study was to investigate the effects of wall materials types on the production of doublelayered and suppressedpungent capsaicin microparticles via spray chilling method. Solidata pdf writer is an easytouse and free pdf portable document format creation tool for windows. Softisan 649 is a partial ester of diglycerin with medium chain fatty acids, isostearic acid, stearic acid, 12 hydroxystearic acid and adipic acid. Then simply follow the prompts provided to complete the download and installation of pc win booster on your pc. Download soda pdf free complex and modernlooking application which enables you to view and edit pdfs, as well as convert these documents to other formats. Jun 16, 1992 softisan 378 is a capriccaprylicstearic triglyceride, as described above. All software on has been tested to ensure its 100% free of spyware, viruses, and other malware. Used in cosmetics in skin care, baby creams, decorative cosmetics and hair care products as lanolin substitute and as a cream base.
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